Visible-Light-Induced Trifluoromethylation of Unactivated Alkenes with Tri(9-anthryl)borane as an Organophotocatalyst

Trifluoromethylation using tri(9-antryl)borane

Abstract

Tri(9-anthryl)borane was successfully applied as an organophotocatalyst for the visible-light-induced trifluoromethylation of unactivated alkenes with CF₃I. The mild reaction conditions tolerated a variety of functional groups, and the reaction could be extended to perfluoroalkylations with C₃F₇I and C₄F₉I. Mechanistic studies revealed that the photoredox catalysis involves an oxidative quenching pathway.

Authors: Jisu Moon, Yu Kyung Moon, Do Dam Park, Sukyung Choi, Youngmin You, Eun Jin Cho*

Link: https://pubs.acs.org/doi/abs/10.1021/acs.joc.9b01624