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C–H Amination Without Metals: Photoredox Diazirination Unlocks a New Class of Nitrogen Building Blocks
Researchers at the Moffitt Cancer Center and the University of South Florida report a metal-free photoredox strategy for C–H amination of...
Tryptophan as a Handle: Cation–Cation Photosensitization for Site-Selective Protein Ligation in Living Cells
A new paper from the Taylor group at the University of Arizona introduces a metal-free, visible-light photosensitization strategy that labels...
Biginelli Dihydropyrimidines as Tunable Alkyl Radical Precursors
A new class of radical precursors from the Janssen-Müller group at Göttingen combines the synthetic accessibility of the century-old Biginelli...
Machine Learning Finds the Right Photosensitizer in 4 Rounds
A new ML framework from Nagoya University uses transfer learning to guide organic photosensitizer screening, cutting the number of experiments...
Inverting MHAT Polarity: Markovnikov Hydrocarboxylation of Styrenes with CO2
A new cobalt-photoredox method from the Teskey group turns the internal carbon of an olefin into a nucleophile, delivering 2-arylpropanoic acids in...
Replacing Mercury Lamps with UV LEDs
A Photochemical Route to Non-Hallucinogenic 5-HT2A Ligands A collaboration between the Mascal Lab at UC Davis, the McCorvy Lab at the Medical...
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