The Brasholz and Francke groups at the University of Rostock and Leibniz Institute for Catalysis report a tandem ketyl radical 3-exo-trig cyclization–lactonization that converts γ-branched δ-oxo acrylates into structurally complex tetracyclic...
The Glorius group at the University of Münster reports a visible-light energy-transfer method for the chemoselective partial saturation of 2-pyridones and their derivatives – a substrate class previously inaccessible to mild photocatalytic...
The Matyjaszewski group at Carnegie Mellon reports a UV-light-driven ATRP method that reaches ≥90% monomer conversion in under 10 minutes, at microliter scale, in open air – enabling high-throughput synthesis of polymer bioconjugates from DNA, RNA,...
When comparing photochemistry LEDs, wattage is the wrong number to look at. What matters is how much light actually reaches your reaction – and on that measure, the EvoluChem 18 W PF LED consistently outperforms 40 W alternatives across the visible...
Researchers at the Moffitt Cancer Center and the University of South Florida report a metal-free photoredox strategy for C–H amination of unactivated substrates using diazirines as the nitrogen source – including the first synthesis of...
A new paper from the Taylor group at the University of Arizona introduces a metal-free, visible-light photosensitization strategy that labels Tryptophan residues with high selectivity in proteins, antibodies, and live cells – all run in the...
A new class of radical precursors from the Janssen-Müller group at Göttingen combines the synthetic accessibility of the century-old Biginelli reaction with redox properties that outperform the standard Hantzsch ester, allowing reactions that...
A new ML framework from Nagoya University uses transfer learning to guide organic photosensitizer screening, cutting the number of experiments needed from 25 down to 4, across a broad range of photoreactions run in the EvoluChem PhotoRedOx Box....
A new cobalt-photoredox method from the Teskey group turns the internal carbon of an olefin into a nucleophile, delivering 2-arylpropanoic acids in one step from styrenes and atmospheric CO2. Metal hydride hydrogen-atom-transfer (MHAT) catalysis is...
A Photochemical Route to Non-Hallucinogenic 5-HT2A Ligands A collaboration between the Mascal Lab at UC Davis, the McCorvy Lab at the Medical College of Wisconsin, and HepatoChem demonstrates how UV LEDs in the Lucent360™ transform a...
The Lucent360™ is the most complete photochemical reactor available for controlling and screening reaction parameters; wavelength, light intensity, reaction time, and temperature at both small and large scale. But specs only matter when you...
