The need for a simple and robust device to perform visible-light photoredox catalysis has become increasingly important. Learn about our setup.
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Featured Article
The impact of high-throughput catalyst screening in drug discovery
The recent trend of chemical catalysis centers and industry-academia partnerships has led to an influx of new reactions with direct applications for medicinal chemists1. High-throughput experimentation (HTE) approaches have significantly lowered...
How do you handle hygroscopic salts?
Salts such as weak bases are omnipresent in organic chemistry. The conversion rate of a reaction can be greatly affected depending on the salt.While it is easy to weigh K2CO3 or Na2CO3. Because salts like Cs2CO3 or K3PO4 are hydroscopic salts, they...
Magic methyl in medicinal chemistry
Methyl groups are very common in drug molecules. As reported by Heike Schonherr and Tim Cernak1, more than half of the top-selling drugs contains a CH3. A simple substitution of a C-H with a methyl can increase the potency of a compound by more...
Buchwald palladium precatalysts
Palladium based catalysis is the most used tool to perform the formation of C-C, C-O and C-N. There are many sources of palladium such as PdOAc2, PdCl2 or Pd2dba3. However the related methods do not always allow sufficient conversion. Palladium...