Methyl groups are very common in drug molecules. As reported by Heike Schonherr and Tim Cernak1, more than half of the top-selling drugs contains a CH3. A simple substitution of a C-H with a methyl can increase the potency of a compound by more...
Palladium based catalysis is the most used tool to perform the formation of C-C, C-O and C-N. There are many sources of palladium such as PdOAc2, PdCl2 or Pd2dba3. However the related methods do not always allow sufficient conversion. Palladium...
Dr Ryan Buzdygon will be presenting "Late-stage functionalization platform for lead optimization and diversification: Generation of high value compounds directly for biological testing" at ACS Boston. Stop by on Wednesday August 19th during the...
HepatoChem will be present at the tenth annual Drug Discovery Chemistry on April 21-23, 2015 in San Diego. Please come and see us at the booth 34. see more information...
Lenexa, KS, August 19th, 2014 -- XenoTech announces an exclusive partnership with HepatoChem to offer fast and cost-effective metabolite production from bioactive small molecules. Based on an innovative and proprietary chemistry platform,...
HepatoChem will be attending the Drug Discovery & Therapy World Congress 2014 from June 16 - June 19 in Boston MA. The event will be held at the Hynes Convention Center located at 900 Boylston Street. Be sure to stop by and visit us at booth...
HepatoChem will be attending the Massachusetts CRO/CMO Symposium on Monday May 5 2014. The event will be held at the Burlington Marriott at 1 Burlington Road, Burlington MA. Be sure to stop by and visit us!
HepatoChem will be attending the New Jersey Drug Metabolism Discussion Group Spring Symposium on May 1, 2014 at The Palace at Somerset Park in Somerset, NJ. Be sure to visit us to hear about our latest technologies!
HepatoChem has developed extensive capabilities to quickly survey organo-metallic chemistry systems and design innovative tools for the pharmaceutical industry. It has most recently commercialized the BMO (BioMimetic Oxidation) Kit, which utilizes...
HepatoChem is mentioned in a recent Bioorganic & Medicinal Chemistry Letters Digest article entitled, 'Emerging technologies for metabolite generation and structural diversification'. Be sure to check out the article at www.sciencedirect.com !...