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Photoredox Iridium–Nickel Dual-Catalyzed Decarboxylative Arylation Cross-Coupling: From Batch to Continuous Flow via Self-Optimizing Segmented Flow Reactor
Abstract Photoredox decarboxylative cross-coupling via iridium–nickel dual catalysis has emerged as a valuable method for C(sp2)–C(sp3) bond...
Photoredox Synthesis of Arylhydroxylamines from Carboxylic Acids and Nitrosoarenes
Abstract Hydroxylamines are found in biologically active compounds and serve as building blocks for the preparation of nitrogen-containing...
PhotoReactor Setup
The need for a simple and robust device to perform visible-light photoredox catalysis has become increasingly important. Learn about our setup.
The impact of high-throughput catalyst screening in drug discovery
The recent trend of chemical catalysis centers and industry-academia partnerships has led to an influx of new reactions with direct applications for...
How do you handle hygroscopic salts?
Salts such as weak bases are omnipresent in organic chemistry. The conversion rate of a reaction can be greatly affected depending on the salt.While...
Magic methyl in medicinal chemistry
Methyl groups are very common in drug molecules. As reported by Heike Schonherr and Tim Cernak1, more than half of the top-selling drugs contains a...
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