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Visible-Light-Induced Trifluoromethylation of Unactivated Alkenes with Tri(9-anthryl)borane as an Organophotocatalyst
Abstract Tri(9-anthryl)borane was successfully applied as an organophotocatalyst for the visible-light-induced trifluoromethylation of unactivated...
Visible Light Promoted Functionalisation of Carbon-Carbon Sigma Bonds
Abstract The use of visible light to activate transition metal catalysts towards redox processes has transformed the way organic molecules can be...
Primary α-tertiary amine synthesis via α-C–H functionalization
Abstract A quinone-mediated general synthetic platform for the construction of primary α-tertiary amines from abundant primary α-branched amine...
Amide Coupling in Medicinal Chemistry
In recent years, amide coupling has become the most frequently used reaction in medicinal chemistry. However there are numerous reagents available.
Enabling synthesis in fragment-based drug discovery by reactivity mapping: photoredox-mediated cross-dehydrogenative heteroarylation of cyclic amines
Abstract In fragment-based drug discovery (FBDD), a weakly binding fragment hit is elaborated into a potent ligand by bespoke functionalization...
Photocatalytic Three-Component Umpolung Synthesis of 1,3-Diamines
Abstract A visible-light-mediated photocatalytic umpolung synthesis of 1,3-diamines from in situ-generated imines and dehydroalanine derivatives is...
PhotoReactors
EvoluChem™ Brand Photoreactors
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