The Matyjaszewski group at Carnegie Mellon reports a UV-light-driven ATRP method that reaches ≥90% monomer conversion in under 10 minutes, at microliter scale, in open air – enabling high-throughput synthesis of polymer bioconjugates from DNA, RNA,...
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Watts Don’t Predict Photon Flux: Why the EvoluChem 18 W LED Outperforms Higher-Wattage Alternatives
When comparing photochemistry LEDs, wattage is the wrong number to look at. What matters is how much light actually reaches your reaction – and on that measure, the EvoluChem 18 W PF LED consistently outperforms 40 W alternatives across the visible...
Tryptophan as a Handle: Cation–Cation Photosensitization for Site-Selective Protein Ligation in Living Cells
A new paper from the Taylor group at the University of Arizona introduces a metal-free, visible-light photosensitization strategy that labels Tryptophan residues with high selectivity in proteins, antibodies, and live cells – all run in the...
Biginelli Dihydropyrimidines as Tunable Alkyl Radical Precursors
A new class of radical precursors from the Janssen-Müller group at Göttingen combines the synthetic accessibility of the century-old Biginelli reaction with redox properties that outperform the standard Hantzsch ester, allowing reactions that...
Machine Learning Finds the Right Photosensitizer in 4 Rounds
A new ML framework from Nagoya University uses transfer learning to guide organic photosensitizer screening, cutting the number of experiments needed from 25 down to 4, across a broad range of photoreactions run in the EvoluChem PhotoRedOx Box....
