{"id":25622,"date":"2018-08-03T17:08:50","date_gmt":"2018-08-04T00:08:50","guid":{"rendered":"https:\/\/hepatochem.com\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/"},"modified":"2018-08-03T17:08:50","modified_gmt":"2018-08-04T00:08:50","slug":"photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals","status":"publish","type":"post","link":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/","title":{"rendered":"Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row admin_label=&#8221;row&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.20.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-8343\" src=\"https:\/\/hepatochem.com\/wp-content\/uploads\/2020\/09\/Screen-Shot-2020-09-01-at-8.14.00-PM-300x186.png\" alt=\"\" width=\"300\" height=\"186\" \/>Abstract<\/strong><\/p>\n<p>The selective functionalization of C(sp3)-H bonds at distal positions to functional groups is a challenging task in synthetic chemistry. Reported here is a photoinduced radical cascade strategy for the divergent functionalization of amides and protected amines. The process is based on the oxidative generation of electrophilic amidyl radicals and their subsequent transposition by 1,5&#8243;H&#8221;atom transfer, resulting in remote fluorination, chlorination and, for the first time, thioetherification, cyanation, and alkynylation. The process is tolerant of most common functional groups and delivers useful building blocks that can be further elaborated. The utility of this strategy is demonstrated through the late&#8221;stage functionalization of amino acids and a dipeptide.<\/p>\n<p><strong>Authors:<\/strong> <span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Morcillo+SP&amp;cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Sara P Morcillo\">Sara P Morcillo<\/a><sup class=\"affiliation-links\"><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-1\">1<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Dauncey+EM&amp;cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Elizabeth M Dauncey\">Elizabeth M Dauncey<\/a><sup class=\"affiliation-links\"><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-1\">1<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kim+JH&amp;cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Ji Hye Kim\">Ji Hye Kim<\/a><sup class=\"affiliation-links\"><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-1\">1<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Douglas+JJ&amp;cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"James J Douglas\">James J Douglas<\/a><sup class=\"affiliation-links\"><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-2\">2<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Sheikh+NS&amp;cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Nadeem S Sheikh\">Nadeem S Sheikh<\/a><sup class=\"affiliation-links\"><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-3\">3<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Leonori+D&amp;cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Daniele Leonori\">Daniele Leonori<\/a><sup class=\"affiliation-links\"><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-1\">1<\/a><\/sup><\/span><\/p>\n<p><strong>Link:<\/strong> <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/anie.201807941\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/anie.201807941<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abstract The selective functionalization of C(sp3)-H bonds at distal positions to functional groups is a challenging task in synthetic chemistry. Reported here is a photoinduced radical cascade strategy for the divergent functionalization of amides and protected amines. The process is based on the oxidative generation of electrophilic amidyl radicals and their subsequent transposition by 1,5&#8243;H&#8221;atom [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":25623,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\">\r\n<html><body><strong><img class=\"alignright size-medium wp-image-8343\" src=\"https:\/\/hepatochem.com\/wp-content\/uploads\/2020\/09\/Screen-Shot-2020-09-01-at-8.14.00-PM-300x186.png\" alt=\"\" width=\"300\" height=\"186\">Abstract<\/strong>\r\n\r\nThe selective functionalization of C(sp<sup>3<\/sup>)\u00e2\u02c6\u2019H bonds at distal positions to functional groups is a challenging task in synthetic chemistry. Reported here is a photoinduced radical cascade strategy for the divergent functionalization of amides and protected amines. The process is based on the oxidative generation of electrophilic amidyl radicals and their subsequent transposition by 1,5\"H\"atom transfer, resulting in remote fluorination, chlorination and, for the first time, thioetherification, cyanation, and alkynylation. The process is tolerant of most common functional groups and delivers useful building blocks that can be further elaborated. The utility of this strategy is demonstrated through the late\"stage functionalization of amino acids and a dipeptide.\r\n\r\n<strong>Authors:<\/strong> <span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Morcillo+SP&cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Sara P Morcillo\">Sara P Morcillo<\/a><sup class=\"affiliation-links\"><span class=\"author-sup-separator\"><\/span><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-1\">1<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Dauncey+EM&cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Elizabeth M Dauncey\">Elizabeth M Dauncey<\/a><sup class=\"affiliation-links\"><span class=\"author-sup-separator\"><\/span><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-1\">1<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kim+JH&cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Ji Hye Kim\">Ji Hye Kim<\/a><sup class=\"affiliation-links\"><span class=\"author-sup-separator\"><\/span><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-1\">1<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Douglas+JJ&cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"James J Douglas\">James J Douglas<\/a><sup class=\"affiliation-links\"><span class=\"author-sup-separator\"><\/span><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-2\">2<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Sheikh+NS&cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Nadeem S Sheikh\">Nadeem S Sheikh<\/a><sup class=\"affiliation-links\"><span class=\"author-sup-separator\"><\/span><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-3\">3<\/a><\/sup><span class=\"comma\">,<\/span><\/span><span class=\"authors-list-item \"><a class=\"full-name\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Leonori+D&cauthor_id=30074300\" data-ga-category=\"search\" data-ga-action=\"author_link\" data-ga-label=\"Daniele Leonori\">Daniele Leonori<\/a><sup class=\"affiliation-links\"><span class=\"author-sup-separator\"><\/span><a class=\"affiliation-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30074300\/#affiliation-1\">1<\/a><\/sup><\/span>\r\n\r\n<strong>Link:<\/strong> <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/anie.201807941\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/anie.201807941<\/a><\/body><\/html>\r\n","_et_gb_content_width":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[680],"tags":[],"class_list":["post-25622","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-featured-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#\\\/schema\\\/person\\\/e095b8d6d9795de228233250261c2cfd\"},\"headline\":\"Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals\",\"datePublished\":\"2018-08-04T00:08:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/\"},\"wordCount\":232,\"publisher\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/hepatochem.com\\\/wp-content\\\/uploads\\\/2020\\\/09\\\/Screen-Shot-2020-09-01-at-8.14.00-PM.png\",\"articleSection\":[\"Featured Article\"],\"inLanguage\":\"en-EU\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/\",\"url\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/\",\"name\":\"Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/hepatochem.com\\\/wp-content\\\/uploads\\\/2020\\\/09\\\/Screen-Shot-2020-09-01-at-8.14.00-PM.png\",\"datePublished\":\"2018-08-04T00:08:50+00:00\",\"inLanguage\":\"en-EU\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-EU\",\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\\\/#primaryimage\",\"url\":\"https:\\\/\\\/hepatochem.com\\\/wp-content\\\/uploads\\\/2020\\\/09\\\/Screen-Shot-2020-09-01-at-8.14.00-PM.png\",\"contentUrl\":\"https:\\\/\\\/hepatochem.com\\\/wp-content\\\/uploads\\\/2020\\\/09\\\/Screen-Shot-2020-09-01-at-8.14.00-PM.png\",\"width\":554,\"height\":344,\"caption\":\"Two pictures of a blue light in the middle of a machine.\"},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#website\",\"url\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/\",\"name\":\"HepatoChem\",\"description\":\"Reinventing Chemistry for Life Sciences\",\"publisher\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-EU\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#organization\",\"name\":\"HepatoChem\",\"url\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-EU\",\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/i0.wp.com\\\/xn8.6f7.myftpupload.com\\\/wp-content\\\/uploads\\\/2019\\\/12\\\/HepatoChem-logo-lowres.png?fit=500%2C89&ssl=1\",\"contentUrl\":\"https:\\\/\\\/i0.wp.com\\\/xn8.6f7.myftpupload.com\\\/wp-content\\\/uploads\\\/2019\\\/12\\\/HepatoChem-logo-lowres.png?fit=500%2C89&ssl=1\",\"width\":500,\"height\":89,\"caption\":\"HepatoChem\"},\"image\":{\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/x.com\\\/evoluchem\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/2420256\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/#\\\/schema\\\/person\\\/e095b8d6d9795de228233250261c2cfd\",\"name\":\"admin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-EU\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c957a93c7d0c8dd066483ae6aed9fb20b222db3695bbe7f027a1baa409d44446?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c957a93c7d0c8dd066483ae6aed9fb20b222db3695bbe7f027a1baa409d44446?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c957a93c7d0c8dd066483ae6aed9fb20b222db3695bbe7f027a1baa409d44446?s=96&d=mm&r=g\",\"caption\":\"admin\"},\"url\":\"https:\\\/\\\/hepatochem.com\\\/euro\\\/author\\\/admin\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/","twitter_misc":{"Written by":"admin","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/#article","isPartOf":{"@id":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/"},"author":{"name":"admin","@id":"https:\/\/hepatochem.com\/euro\/#\/schema\/person\/e095b8d6d9795de228233250261c2cfd"},"headline":"Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals","datePublished":"2018-08-04T00:08:50+00:00","mainEntityOfPage":{"@id":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/"},"wordCount":232,"publisher":{"@id":"https:\/\/hepatochem.com\/euro\/#organization"},"image":{"@id":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/#primaryimage"},"thumbnailUrl":"https:\/\/hepatochem.com\/wp-content\/uploads\/2020\/09\/Screen-Shot-2020-09-01-at-8.14.00-PM.png","articleSection":["Featured Article"],"inLanguage":"en-EU"},{"@type":"WebPage","@id":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/","url":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/","name":"Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals","isPartOf":{"@id":"https:\/\/hepatochem.com\/euro\/#website"},"primaryImageOfPage":{"@id":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/#primaryimage"},"image":{"@id":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/#primaryimage"},"thumbnailUrl":"https:\/\/hepatochem.com\/wp-content\/uploads\/2020\/09\/Screen-Shot-2020-09-01-at-8.14.00-PM.png","datePublished":"2018-08-04T00:08:50+00:00","inLanguage":"en-EU","potentialAction":[{"@type":"ReadAction","target":["https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/"]}]},{"@type":"ImageObject","inLanguage":"en-EU","@id":"https:\/\/hepatochem.com\/euro\/photoinduced-remote-functionalization-of-amides-and-amines-using-electrophilic-nitrogen-radicals\/#primaryimage","url":"https:\/\/hepatochem.com\/wp-content\/uploads\/2020\/09\/Screen-Shot-2020-09-01-at-8.14.00-PM.png","contentUrl":"https:\/\/hepatochem.com\/wp-content\/uploads\/2020\/09\/Screen-Shot-2020-09-01-at-8.14.00-PM.png","width":554,"height":344,"caption":"Two pictures of a blue light in the middle of a machine."},{"@type":"WebSite","@id":"https:\/\/hepatochem.com\/euro\/#website","url":"https:\/\/hepatochem.com\/euro\/","name":"HepatoChem","description":"Reinventing Chemistry for Life Sciences","publisher":{"@id":"https:\/\/hepatochem.com\/euro\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/hepatochem.com\/euro\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-EU"},{"@type":"Organization","@id":"https:\/\/hepatochem.com\/euro\/#organization","name":"HepatoChem","url":"https:\/\/hepatochem.com\/euro\/","logo":{"@type":"ImageObject","inLanguage":"en-EU","@id":"https:\/\/hepatochem.com\/euro\/#\/schema\/logo\/image\/","url":"https:\/\/i0.wp.com\/xn8.6f7.myftpupload.com\/wp-content\/uploads\/2019\/12\/HepatoChem-logo-lowres.png?fit=500%2C89&ssl=1","contentUrl":"https:\/\/i0.wp.com\/xn8.6f7.myftpupload.com\/wp-content\/uploads\/2019\/12\/HepatoChem-logo-lowres.png?fit=500%2C89&ssl=1","width":500,"height":89,"caption":"HepatoChem"},"image":{"@id":"https:\/\/hepatochem.com\/euro\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/x.com\/evoluchem","https:\/\/www.linkedin.com\/company\/2420256"]},{"@type":"Person","@id":"https:\/\/hepatochem.com\/euro\/#\/schema\/person\/e095b8d6d9795de228233250261c2cfd","name":"admin","image":{"@type":"ImageObject","inLanguage":"en-EU","@id":"https:\/\/secure.gravatar.com\/avatar\/c957a93c7d0c8dd066483ae6aed9fb20b222db3695bbe7f027a1baa409d44446?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c957a93c7d0c8dd066483ae6aed9fb20b222db3695bbe7f027a1baa409d44446?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c957a93c7d0c8dd066483ae6aed9fb20b222db3695bbe7f027a1baa409d44446?s=96&d=mm&r=g","caption":"admin"},"url":"https:\/\/hepatochem.com\/euro\/author\/admin\/"}]}},"jetpack_featured_media_url":"https:\/\/hepatochem.com\/wp-content\/uploads\/2020\/09\/Screen-Shot-2020-09-01-at-8.14.00-PM.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/posts\/25622","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/comments?post=25622"}],"version-history":[{"count":0,"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/posts\/25622\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/media\/25623"}],"wp:attachment":[{"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/media?parent=25622"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/categories?post=25622"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hepatochem.com\/euro\/wp-json\/wp\/v2\/tags?post=25622"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}